Endocrine Abstracts

Hypopituitarism is relatively rare disorder characterized by different kind of pituitary deficit, and GH-deficiency as well as hypogonadotropic hypogonadism (HH) are the most often met ones. The prevalent cause of hypopituitarism is organic lesion of hypothalamo-pituitary region (pituitary tumors, craniopharyngiomas, empty sella turcica and etc). Successful neurosurgery and optimal replacement hormonal treatment allow patients to appeal to a doctor about pregnancy. Results of ...

In purpose to characterize the disturbances of menstrual function in acromegalic women of reproductive age, we investigated 19 women with de novo acromegaly diagnosed at the age of 19–37 (median age 28) years. Before diagnosis, an average duration of acro-signs was 3.8 years, after diagnosis we observed women for 5 years. Among the first meaningful symptoms menstrual irregularities and/or infertility were noted in 13 (73.7%) cases. Initial levels of GH were 71 (3...